The Gut Bacteria & Alzheimers Disease

Two completely different body functions 'and an short explanation why one is affected by the other, and its importance for a better health later in life.

Ricardo Mazcal

4/10/20223 min read

The healthy human (gut) microbiome. We humans are virtually identical in our genetic makeup, yet the small differences in our DNA give rise to the observable characteristics of an individual resulting from the interaction of its genotype with the environment and the diversity across the human population.In contrast, the Metagenome of the human microbiome—the total DNA content of microbes inhabiting our bodies—is quite a bit more variable, with only a third of its constituent genes found in a majority of healthy individuals. Understanding this variability in a healthy microbiome has been a major challenge in microbiome research, dating back at least to the 1960s. Cataloging the necessary and sufficientsets of microbiome features that support health, and the normal ranges of these features in healthy populations is an essential first step to identifying and correcting microbial configurations that are implicated in disease, play a role in how our bodies work, affecting everything from allergies to obesity. Researchers found through gene-expression studies that gut microbes regulated the activity of a gene essential to the production of serotonin, a critical brain chemical. Research also dissected out major regions of the brain and measured gene activity in each region and found differences in activity and anxiety levels.Are you a worrier? Low on energy? You might be able to blame your state of mind on the bugs in your gut.Researchers studying behavior and gene activity in mice have found that these microbes appear to helpshape brain development. These findings could lead to new ways to treat depression, anxiety, and othermental disorders. How these results might translate into therapies for mental illness is still uncertain. But, the findings point to "clear effects of the microbiome on brain development and behavior," says John Bienenstock,an immunologist at McMaster. Researchers tell us that neurodevelopmental disorders [such as schizophrenia]may be profoundly influenced by the microflora in the gut. The presence of microbes also reduced the amountsof two proteins important to nerve-cell maturation, suggesting how the microbiome leads to the differences in behavior. During pregnancy, gut microbes may release chemicals that affect fetal brain development, the researchers say. The bottom line is to do all imaginable to have a healthy gut.Ways to Strengthen Your MicrobiomeHuman Microbiome is a complex internal ecosystem of microbes/bacteria located within our digestive systemthat we commonly call the gut. The word "microbiome" is two words "micro," meaning small and "biome" is a habitat of living things. The human microbiome consists of 100 trillion symbiotic microbial cells buried in the gut of each person. Our individual microbiome is called our Genetic Footprint since it determines our unique DNA(hereditary factors). The microbiome is different from other organs and has very far-reaching results tied to many varied bodily functions. About 90 percent of all diseases can be traced back to the gut and the health of the microbiome. These diverse organisms help govern nearly every function of the human body. The importance of our gut microbiome cannot be overstated: Poor gut health can contribute to autoimmune diseases and many other disorders like arthritis, dementia and as the research data above states, it also impacts Alzheimer's, heartdisease, and cancer. Our health, fertility, and longevity depend on the balance of good andbad bacteria living within our gut. We shape our own microbiome from what we eat; ourbacteria adapt to changes in our environmen, So how can you improve your gut microbiome? Add probiotics to your diet, either through eating probiotic-rich foods or taking supplements like Maz-mix containing live microorganisms that maintain or restore beneficial bacteria to the digestive tract. In addition, make sure to eat your vegetables, cut out sugar and avoid processed foods. Cut back on red meat, Sleep at least 7 hours, Avoid antibiotics. Antibiotic use can have negative effects on the gut microbiota, including reduced species diversity, altered metabolic activity, and theselection of antibiotic-resistant organisms, which in turn can lead to antibiotic-associated diarrhea and other recurrent infections. Stock up on dietary sources of prebiotics; fermented foods are gut-friendly. Probiotics with prebiotics are great for your gut - Maz-mix digestive formula has the most significant amounts of both. If you have any comments or questions about this column, contact me by email ( I invite you to visit my Website: or find me at the Cuale Island Friday Market from 9 am to 1:30 pm. You will find herbal supplements, tinctures, tonics and many natural products such as organic coffees, apple cider vinegar with the Mother, and 38 different spices, including turmeric and Ceylon cinnamon. Superfoods such as Spike Protein Detox, Golden Tea, Indulge chocolate with 70% cocoa, Veggie Power, Maz-mix digestive formula, and Longevity strategy capsules.